Wavelength-dependent Stimulation of Wound Healing Factors

Warning: technical jargon ahead

Note: The Vari-Chrome Pro may provide non-healing wounds with a restart of healing or an acceleration of healing. One aim of the therapy is to enable the standard of care to efficiently bring the wound to closure. This page is about the first seconds to minutes when wounds respond to the variable wavelength therapy, even after months or years.

How many ways might a wound stop healing?

More than 8M American lives are affected by wounds. Healing may slow, stop, or reverse depending upon a multitude of factors. Each type of wound may stall at any stage in a myriad of possible configurations.

  • 8.2M wounds cost Medicare between $28-96B/year

  • 2.5M pressure ulcers cost $11B/year

  • 26.8M adults with diabetes face a19-34% lifetime risk of foot ulcers

Wound care specialists may mechanically scrape the wound surface with the hope of restarting healing marked by fresh blood, called exudates.

At other times, maggots or a stream of water may be used to remove debris.

Unfortunately, the complexity of wounds healing themselves presents the practitioner with uncertainty as to what interventions that the wound might need to resume healing.

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Could a few photons accelerate wound healing?

 

Photobiomodulation using fixed wavelengths has been shown to accelerate wound healing by reducing inflammation, increasing circulation, and antimicrobial action. However, the particular fixed wavelengths being applied might not be ones needed at that moment in time.

Some bioactive molecules respond only to precise wavelengths. A 10nm miss in the wavelength may result in success or failure. The molecules, called chromophores, select which photons to absorb and not the other way around.

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Could "no missing wavelengths" be the key?

 

The Vari-Chrome® Pro addresses these uncertainties by sequentially presenting the wound with photons with varying properties. At any instant, the beam includes a few wavelengths while excluding other wavelengths that might compete with the  stimulation. All with no missing wavelengths.

A molecule must absorb a photon to begin a cascade of signaling. The photon deposits its quantum of energy and exists no more. The action takes less than a trillionth of a second. Then, unknown "factors" signal that it's time to resume healing.

The Vari-Chrome beam varies with no missing wavelengths. This is important because the variation may sequentially stimulate different molecules.

For example, the #2 Selection varies the wavelength over a range wherein hemoglobin molecules deferentially absorb photons depending upon its oxygenation state. Pulse oximeters use the differences in absorption at different wavelengths to measure the oxygenation of the blood.

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Take the wound care specialist to the patient

Now patients living in at home, rural, or remote areas may have state-of-the-art wound care via telemedicine. The wound care specialist may now watch the restart of wound healing in real time. Their observations, via a smart phone link, might lead to saving limbs without the patient traveling to a specialty clinic.

Multi-spectral recordings of fresh exudates in moist wounds may confirm progress, or not. Healing may resume without an immediate visible marker.

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