What’s “Instant” about the Instant Verification System?

 Warning: technical jargon ahead

 

Building Models

Wandering through our website, you may be wondering about the crazy fast responses of volunteers with treatment-resistant pain and impaired functions. We did too. We still wonder.

As engineers, we’re comfortable with change-of-state events, responses, and outcomes. We prefer tangible measures, such as skin temperatures. Time is measured in milliseconds, not visits. We shy away from imaginary pain scales used in medicine.

Engineers build models to communicate ideas without needing to know all the details. Models let people discuss complex problems from different perspectives. PhotoMed’s team developed the Instant Verification System™ to document details of unexpected events that might help make PhotoMed’s therapy more effective and efficient. The result is the Triple 2 Algorithm.

Two Models

PhotoMed’s team wondered, “why do conventional randomized controlled trials examine modulation or “management” of pain rather than ending it?”

Could PhotoMed’s studies be different in some fundamental way? Ultimately, to models emerged that “explain” the differences.

Two Models 2019-07-10.png
 

You may be thinking that the two models appear to conflict.

They don’t.

The two models describe outcomes for different people.

 

How long can an “interruption” of normal function last?

Skin Temperature Regulation System

Have your hands ever gone numb upon being chilled? What happened to the numbness when they warmed?

Wouldn’t you be surprised by the warming if your hands had remained unpleasantly cold for 30 years?

You might watch this clip from the “instant” perspective. Could the warming response mark the end of the interruption? How long did it take for the warming response to become measurable?

“Robert” (below) was surprised and so were his co-workers when he no longer needed to turn up the heat to feel less chilled.

Did you notice that the therapy was delivered to Robert’s neck rather than to his hands?

(Clip = 14 seconds) (Lighter gray is warmer) It’s a duplicate so that you don’t have to leave this page.

 

Sensory System

Could numb hands or feet give up sending sensory signals? Or, does your brain ignore the unpleasant signals? How long could the signals be ignored? For 8 years?

For 42 years, “George” experienced the effects of diabetes. For the last 8 years, he couldn’t feel his feet. He had to look at his feet to keep his balance while walking. He enrolled in a study by William Conard, M.D. developing PhotoMed’s therapy to learn if the therapy might relieve his back pain.

“George’s” testing started about 6 minutes after therapy began during his second visit. George was surprised when he began to feel his feet again. That was cool.

But did he know where he was being touched?

One problem. His perceived touch locations were not aligned with his feet.

The maps needed reconstruction.

Watch his testing with von Frey monofilatments. (Clip = 13 Seconds)

 

There is more to this story. See the neuroscience page to watch George’s touch-maps realign with his skin.

Anesthesiologists, neurologists, and other researchers who used the Instant Verification System™ frequently mentioned the patient’s surprise in their notes.


Motor System - “locked-in” from a stroke

For 14 years, Josephine experienced the “locked-in syndrome” after a brain-stem stroke.

Josephine was fully alert and able to feel her body, but she could only elevate her left eye to communicate her thoughts and needs.


Josephine enrolled in Dr. Conard’s Vari-Chrome development study to see if the therapy might help her move a bit. Would 2 visits be enough to determine failure? (Clip = 21 seconds)

 

After her second visit, Josephine achieved incremental improvements, but more slowly than the first.

The Instant Verification System™ documented her improvements over the next few weeks. You can read about some of Josephine’s achievements in the neuroscience page.

Perhaps some researchers might find out how and why. Perhaps some of the 1200 recordings with responses, out of 3600, can help the researcher get started.