The responses were crazy fast, and we couldn’t make heads or tails out of them

By Allan Gardiner

Warning: technical jargon ahead

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 The real-time recordings suggest that the events take zero time. That’s hard to believe, so we call it 2 seconds. Maybe this seems weird.

But what is weird about the body returning back to normal?

Why did it switch back-to-normal so fast?

The responses also seemed too large. None of our anesthesiologist or neurologist advisors that we consulted had an explanation for the observations. Our engineering models didn’t explain anything other than “it works” as recorded in real time. (1) So, this was frustrating. We wanted to some to figure out why it works.

Could it be just that the body completes some stuck task as it had been trying to do all along?

Could the perception be different from the facts? (2)

Despite not knowing why, maybe it is time to get more people to benefit from ultra-low cost care. The “back to normal” event disrupts the conventional ongoing attempts to “manage” the patient’s pain. The event appears to end the endless cycle of “nothing worked” pain.

 
 
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Machine learning found that the unexpected responses appear to be the same irrespective of the disorder, its duration, or intensity. This was totally inconsistent with the current medical paradigm. How could a few photons with varying quantum properties do so many seemingly different things? To our software engineers, this frustration felt like an “illegal command”.

The photons were too good. The “nothing worked” pain resolved in about 1 in 3 cases. The team kept trying more disorders to get more failures. They needed failures to adjust their models. Their studies included people that they were sure that nothing beneficial would happen. To the team’s frustration, these disorders responded at the same rate. Link to Disorders Page


As the algorithm improved, at least it was taking less time to detect when therapy didn’t work.

The engineers measured TIME in their real-time recordings. As the therapy improved, the time to achieve relief, or not, appeared to shrink. But to zero? That didn’t make sense. The investor’s how it works slide remained blank for almost 20 years. That’s a long time for events that seem to take no time at all.

They went back to the drawing board before they had heard about machine learning. They poured over the chunky data. There seemed to be holes in every explanation. Yet patients were getting better beyond any reasonable expectation. Much better. Were the non-invasive therapy outcomes breaking rules of medicine?

They surely weren’t predicted.

The chronic pain patients had already tried many invasive interventions without lasting relief. Each intervention “ruled-out” some reason for their pain’s presence and intensity. That is “nothing worked” to relieve them. Could they be expected to improve?

PhotoMed’s team developed an algorithm that became more efficient with the machine learning evaluating new data.

The algorithm worked like mom’s adage, if at first you don’t succeed then try again. See TX1 - TX4 in the Figure below. The logic was the same as for invasive interventions, but 1000s of times faster.

Would the patient respond to 1, 2, or a sequence of different quantum properties?

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No matter how we tried, the algorithm appears to be stuck. This is all that this therapy is likely to do. We do not expect improvements in the future.

We would be very grateful for research that might explain the consistently observed responses and outcomes.

The following examples are nothing special. The real-time recordings demonstrate what happens in 33% of cases (not more, unfortunately). The results have been and can easily be reproduced.

Phantom pain

Could phantom pain only be treated with spooky medicine? Currently, mirrors are used to reprogram the brain over many exposures. That takes a lot of time and effort. The process is called neuroplasticity. (3)(4)

Unfortunately, the back-to-normal responses appear to be too fast to align with current theories of neuroplasticity. We wish that neuroplasticity could provide the explanation that would let us move on.

The problem of phantom pain may be wide-spread because of its association with “post-surgical” pain. The intensity of the pain appears to be disrelated to the size of the physical area removed. For example, about 1 in 8 people who have had a knee replacement end up with pain that makes them wish that they had their old pain back. The patient and practitioner can know in 2 visits whether PhotoMed’s therapy might help, or not.

Sometimes the phantom pain or sensations involves the misalignment of perceived touch. For most people, realignment occurs automatically without being noticed. It’s normal to return back-to-normal. That is, it shouldn’t be surprising no matter when it happens.

Perhaps smarter people than us will find out how the misalignment pain and sensations can last decades. As software and hardware engineers, we just make tools that let others see the responses.

Want to watch?

Chasing away the phantoms

“George” progressively couldn’t feel his feet for the past 8 years. The numbness was thought to be an effect of 40+ years of diabetes. (5)(6)(7)(8)(9)

The phantoms had stolen his sensation:

  • George shuffled and watched his totally numb feet when he arrived for his first visit.

  • After PhotoMed’s therapy during his first visit, he vaguely felt sensations from heavy pressure applied to his left foot.

  • During his second visit, George was asked to NOT move or look at his feet. He complied.

  • Within minutes, his sensation returned to near-normal. However, he couldn’t correctly identify where he was being touched.


Watch the monofilament testing during his second visit. (46 seconds)

Link to Restoration of Sensation Page with more of George’s story.


Mirror-neuron Synesthesia

Sometimes PhotoMed’s therapy appears to do an incomplete “uninstall” of phantom pain. The pain is gone. Their frozen shoulder feels fine. However, when they go to the gym and observe other people pushing weights, they feel their old pain, but only when watching.

Additional PhotoMed therapy has not been proven effective for this problem, called mirror-neuron synesthesia. About 10% of the people who responded to PhotoMed’s therapy reported having this “gym” phantom pain.

One five-minute session of mirror-neuron synesthesia therapy could resolve the problem to complete the “uninstall” of their pain.

This is what happened to Lois’s “gym” pain after PhotoMed’s therapy took care of her thumb pain. (46 seconds)

Link to more details about Lois’s mirror-neuron synesthesia.

 

Abnormal skin-temperature regulation

Cold hands make it easy to observe one of the body’s basic functions. Thermal imaging lets us watch as cold hands warm. There is nothing special about warming. Unless your hands have been cold for 30 years.

PhotoMed’s therapy has been prompting this warming in about 1 in 3 people with cold limbs. The warming and back-to-normal function appear to relieve pain associated with the coldness.

Because the awareness of temperature normally fades, could a stuck perception of coldness be the problem?


Further reading

(1) http://www.buonomanolab.com/ Buonomono D, Your Brain is a Time Machine: the Neuroscience and Physics of Time, W.W Norton & Company (2018)

(2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852534/  Zacks JM, Speer NK, Swallow KM, Braver TS, Reynolds JR. Event perception: a mind-brain perspective. Psychol Bull. 2007;133(2):273–293. doi:10.1037/0033-2909.133.2.273

(3) Ramachandran, VS (2011). The Tell-Tale Brain: A Neuroscientist's Quest for What Makes Us Human. New York: W. W. Norton & Company.

(4) http://cbc.ucsd.edu/pdf/neurocog_synesthesia.pdf Hubbard, EM, & Ramachandran, VS (2005). Neurocognitive Mechanisms of Synesthesia. Neuron, 48(3), 509-520.

(5) https://www.cdc.gov/diabetes/data/statistics-report/deaths-cost.html

(6) https://care.diabetesjournals.org/content/early/2018/03/20/dci18-0007 Economic Costs of Diabetes 2017

(7) http://pharmrev.aspetjournals.org/content/64/4/880 Diabetic Peripheral Neuropathy: Should a Chaperone Accompany Our Therapeutic Approach

(8) https://www.frontiersin.org/articles/10.3389/fnana.2014.00079/full Diabetic neuropathy and sensory apparatus “meissner corpuscle and merkel cells”

(9) https://www.sciencedirect.com/science/article/pii/S1017995X16304072?via%3Dihub Factors affecting lifespan below-knee amputation in diabetic patients